Valium 10 mg

Valium® (Diazepam) 10mg – The Gold-Standard Benzodiazepine for Acute Symptom Control

Trusted anxiolytic, muscle relaxant, and anticonvulsant with decades of clinical validation

Premium Therapeutic Benefits

✔ Rapid Anxiety Relief – Noticeable calm within 30 minutes
✔ Verlengde duur – Active metabolites provide prolonged effects (up to 48 hours)
✔ Versatile Administration – Oral, IV, IM, or rectal (for seizures)
✔ Muscle Relaxation – Direct action on spinal cord reflexes

Optimal Clinical Uses

• Acute panic attacks (short-term crisis management)
• Verlichting van spierspasmen – Especially back injuries/spinal conditions
• Alcohol withdrawal protocol (CIWA-Ar guideline recommended)
• Pre-procedure sedation (dentistry/endoscopy)
• Seizure emergencies (when IV access unavailable)

Precision Dosing Guide

• Standard Adults: 2-10 mg 2-4x per dag (maximaal 30 mg/dag)

• Elderly/Debilitated: 2-5mg 1-2x daily

• Status epilepticus: 5-10mg IV every 10-15min PRN

• Halveringstijd: 20-100 hours (including active metabolites)

Exclusive Advantages

→ Proven reliability since 1963 (original benzodiazepine)
→ Smooth taper profile due to long-acting metabolites
→ Flexible formulations – Tablets, injection, rectal gel
→ Kosteneffectief – Multiple generic options available

Safety-First Features

⚠️ DEA Schema IV – Requires vigilant prescribing
⚠️ Boxed Warning:

• Risk of fatal respiratory depression with opioids

• Potential for dependence/addiction

• Neonatal withdrawal syndrome

Patient-Specific Considerations

• Best for: Short-term use (<2-4 weeks)
• Vermijd in: Severe hepatic impairment, untreated OSA
• Critical Interaction: Opioids, alcohol, CYP3A4 inhibitors
• Stopzetting: Must taper to prevent withdrawal

Identificatie en verpakking

• Merktabletten: Blue, scored, “VALIUM 10” imprint

• Generieke geneesmiddelen: Multiple manufacturers (same bioequivalence)

• Hospital Formulations:
  • 5mg/mL injectable vials
  • Diastat® rectal delivery system